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In Texas, this means at least a dozen babies each year are identified with SCID who may have otherwise been missed. (Figure 4.) The SCID Newborn Screening confirms the frequency of SCID is approximately 1 out of every 40,000 live births. A number are in the pilot stage and do plan for SCID screening to begin, but there are two states, Indiana and Louisiana, that remain without SCID screening or planning. However, this still leaves some states without screening for SCID. (Figure 3., A & B) In 2008, a nationwide campaign for SCID screening started in Wisconsin and now most states across the nation, including Texas, have adopted screening for SCID via the Guthrie Card tests. Today, we celebrate a new way of identifying SCID in babies right from birth through the SCID newborn screen that tests for the baby’s T cells in the form of T-cell Receptor Excision Circles ( TRECs) through the newborn heel-stick blood sample on the Guthrie Card. T-cell Receptor Excision Circles (TRECs) analysis, abnormal result requires timely confirmatory test with an immunologist
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Newborn Screen heel-stick blood sample placed onto the Guthrie Card.